Museveni has commissioned works to upgrade the Ntungamo-Mirama Hill Road in Ntungamo District.
The 37km road connects three sub-counties of Ntungamo, Rwikinoro and Ruhama and links Uganda to Kigali, Rwanda via Nyagatare and Umutara districts.
The route is shorter compared to the one of Ntungamo-Kabale- Katuna- Kigali.
The Ntungamo-Mirama Road was popular in the 70s but was destroyed by the Tanzania forces fighting former President Idi Amin.
Works will involve upgrading the road to Bitumen standard from murram.
The carriageway will be seven meters wide while the shoulders will be 1.5 meters. Towns along the road like Kafunjo, Sofiya, Kakukuru and Ruhama will be provided with 2.5 meters wide parking lanes and two meters wide with raised shoulders.
While commissioning works on Monday in Ruhama, President Museveni said the road will facilitate trade, urging Ugandans to use it as they try to pull themselves out of poverty.
“We have brought power and built roads. What is remaining is you to fight poverty in your homes,” Mr Museveni said.
Ruhama MP and minister for Karamoja Janet Museveni hit at critics who she said had been blaming her for failing to deliver on the project.
“You know how long we have been waiting for this road. Many of you have said a lot but I believe those who have been claiming that I failed to deliver will now have nothing to say,” Ms Museveni said.